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What to consider when facing a biologic

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Talking about changes to our autoimmune treatment can be overwhelming—especially if the conversation turns to biologics. Many people managing rheumatoid arthritis (RA) or other autoimmune diseases find themselves in a rheumatologist’s office, hearing that a biologic might be the next best step. So, what exactly are biologics, and how can you make the best decision for yourself? Let’s dive into the basics and explore some key questions to ask so you can feel more comfortable with whatever path you choose.

What Are Biologics?

Biologics are a class of medications that have brought a whole new level of specificity to autoimmune treatment. Unlike traditional drugs, biologics are made from living organisms—proteins, antibodies, or cells—which scientists isolate and modify to target specific aspects of the immune system. For people with autoimmune diseases, these medications can help reduce inflammation and limit the immune system’s overactivity that causes joint damage.

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Why Primary Care is Essential for Autoimmune Patients

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Managing an autoimmune condition can be complex and overwhelming, especially when you’re frequently visiting your rheumatologist. However, it’s crucial not to overlook the importance of your primary care doctor (PCP). Let’s explore how a good relationship with your PCP can benefit your heart health, coordinate your care, and keep you up-to-date on vaccinations.

The Importance of Cardiovascular Health

Heart health is a critical aspect to monitor when living with an autoimmune condition. Conditions like rheumatoid arthritis, lupus, and psoriatic arthritis increase the risk of cardiovascular disease due to chronic inflammation. Your PCP is essential in regularly checking your blood sugar, cholesterol, blood pressure, and weight, ensuring these risk factors are controlled.

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Rheumatology Appointments, Morning Stiffness & Joint Pain

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Let’s delve into some crucial topics brought up by my newsletter readers: how to handle the wait for your rheumatology appointments, the mystery of morning stiffness, and dealing with joint pain. 

Palindromic Arthritis: A Closer Look

One of the most intriguing conditions I frequently encounter is palindromic arthritis. This type of inflammatory arthritis comes and goes, causing intense but short-lived joint inflammation and pain. It tends to affect the joints of your hands, fingers, knees, and shoulders. Unlike gout or CPPD (pseudogout), which can have similar symptoms, palindromic arthritis doesn’t involve crystals in the joint fluid. Instead, it affects the structures around the joint, like tendons and ligaments.

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HLA-B27: What It Means for Ankylosing Spondylitis and Arthritis

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If you’ve recently heard about the HLA-B27 test or had it done, you might be wondering what it really means for your health. It’s one of the many autoimmune tests that can be confusing—especially when you get a positive result and then hear your doctor say, “Oh, that doesn’t mean anything.” So, what exactly is HLA-B27, and why does it matter when it comes to arthritis and conditions like Ankylosing Spondylitis?

What Is HLA-B27?

HLA-B27 is a gene that produces proteins involved in your immune system. These proteins play a key role in helping your immune cells communicate with each other, which is crucial for maintaining a healthy immune response. Now, HLA-B27 is not the only gene involved in building a healthy immune system, but it has caught a lot of attention because of its connection to certain types of arthritis, especially Ankylosing Spondylitis.

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