Understanding the Rheumatoid Factor (RF) and its relationship with Rheumatoid Arthritis (RA) isn’t as easy as the names imply. You might think that a positive RF test result spells out RA without a doubt, but as with most things autoimmune, it’s not that simple.
The Rheumatoid Factor autoantibody
The Rheumatoid Factor is an autoantibody, which means it’s a protein produced by our immune system that mistakenly attacks our own tissues. Our immune system is constantly producing autoantibodies, however we also have a built-in regulatory system that finds these autoantibodies and destroys them – making sure they don’t cause trouble. When an autoimmune condition, like Rheumatoid Arthritis develops, it’s because our regulatory system is faltering and isn’t doing a good job of getting rid of autoantibodies and other autoimmune factors.
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